Discontinue Qsymia in patients who experience suicidal thoughts or behaviors. Qsymia is not recommended in patients with a history of suicidal attempts or active suicidal ideation. Acute angle closure glaucoma has been reported in patients treated with topiramate, a component of Qsymia. Symptoms typically occur within 1 month of initiating treatment with topiramate but may occur at any time during therapy. The primary treatment to reverse symptoms is immediate discontinuation of Qsymia.
Elevated intraocular pressure of any etiology, if left untreated, can lead to serious adverse events including permanent loss of vision. Qsymia can cause mood disorders, including depression and anxiety, as well as insomnia.
Patients with a history of depression may be at increased risk. For clinically significant or persistent symptoms consider dose reduction or withdrawal of Qsymia. Qsymia can cause cognitive dysfunction e. Since Qsymia has the potential to impair cognitive function, patients should be cautioned about operating hazardous machinery, including automobiles.
Hyperchloremic, non-anion gap, metabolic acidosis has been reported in patients treated with Qsymia. Measurement of electrolytes including serum bicarbonate prior to starting Qsymia and during Qsymia treatment is recommended.
If metabolic acidosis develops and persists, consideration should be given to reducing the dose or discontinuing Qsymia. Qsymia can cause an increase in serum creatinine that reflects a decrease in renal function glomerular filtration rate.
In phase 3 trials, peak increases in serum creatinine were observed after 4 to 8 weeks of treatment. On average, serum creatinine gradually declined but remained elevated over baseline creatinine values. The changes in serum creatinine and measured GFR with short-term Qsymia treatment appear reversible with treatment discontinuation, but the effect of chronic treatment on renal function is not known. Therefore, measurement of serum creatinine prior to starting Qsymia and during Qsymia treatment is recommended.
If persistent elevations in creatinine occur while taking Qsymia, reduce the dose or discontinue Qsymia. Qsymia has not been studied in combination with insulin. Measurement of blood glucose levels prior to starting Qsymia and during Qsymia treatment is recommended in patients with type 2 diabetes. A reduction in the dose of antidiabetic medications which are non-glucose-dependent should be considered to mitigate the risk of hypoglycemia.
In hypertensive patients being treated with antihypertensive medications, weight loss may increase the risk of hypotension. Measurement of blood pressure prior to starting Qsymia and during Qsymia treatment is recommended in patients being treated for hypertension.
If a patient develops symptoms associated with low blood pressure after starting Qsymia, appropriate changes should be made to the antihypertensive drug regimen. The concomitant use of alcohol or central nervous system CNS depressant drugs e. Therefore, avoid concomitant use of alcohol with Qsymia. It is thought to reduce your appetite — giving you all-day hunger control.
Hunger comes on gradually and is the desire for any type of food. However, cravings can come on suddenly and are the desire for a specific type of food. They can also be tied to emotions like boredom. Qsymia keeps working throughout the day to help you feel full. It may also alter the taste of certain foods, which may reduce the pleasure of eating. When it comes to trying to lose weight, almost half of 3, patient responses indicated that the statement they related to the most was:.
Qsymia Patient Survey: Online survey conducted in August Responses from 3, Qsymia patients, 18 years or older. Respondents were not remunerated for participating in the survey. Infographic: Hunger vs Cravings. Hunger vs. Lose weight and keep it off with diet, exercise and once-daily Qsymia.
Qsymia can help you take control of the hunger and cravings you struggle with. Qsymia is clinically proven to help patients lose weight and inches off their waist. Additional shipping and handling costs will apply. Please see QsymiaEngage. Qsymia should be used together with a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index BMI of:.
Do not take Qsymia if you are pregnant, planning to become pregnant, or become pregnant during Qsymia treatment; have glaucoma; have thyroid problems hyperthyroidism ; are taking certain medicines called monoamine oxidase inhibitors MAOIs or have taken MAOIs in the past 14 days; are allergic to topiramate, sympathomimetic amines such as phentermine, or any of the ingredients in Qsymia.
See the end of the Medication Guide for a complete list of ingredients in Qsymia. If you take Qsymia during pregnancy, your baby has a higher risk for birth defects called cleft lip and cleft palate. These defects can begin early in pregnancy, even before you know you are pregnant. Patients who are pregnant must not take Qsymia. Patients who can become pregnant should have a pregnancy test before taking Qsymia and every month while taking Qsymia and use effective birth control contraception consistently while taking Qsymia.
Talk to your healthcare provider about how to prevent pregnancy. If you become pregnant while taking Qsymia, stop taking Qsymia immediately, and tell your healthcare provider right away. Increases in heart rate. Qsymia works best when combined with a reduced-calorie diet.
Consume a diet consisting of plenty of fruits and vegetables, whole grains, lean protein, and healthy fats. Limit saturated fats and added sweeteners. You should take Qsymia for as long as your healthcare provider has prescribed. If you experience side effects, be sure to speak to your doctor to see if stopping the medication is best. Do not stop taking the medication on your own without consulting your doctor, as this can cause adverse side effects.
Qsymia starts to work immediately after you take it to reduce hunger and cravings. But it will take several days or weeks for you to lose weight resulting from a reduced appetite. Talk with your doctor about what to expect. Talk to your doctor about the potential health benefits of losing weight with Qsymia. Discussing your specific medical history and future plans will help you make the best decision with your provider.
It's important to remember that no pill can take the place of a balanced diet and regular physical activity.
Not every medication works the same way for everyone. Monitoring your progress with your doctor will help you stay safe and avoid negative side effects.
Get one simple hack every day to make your life healthier. Food and Drug Administration. Medications target long-term weight control.
Updated July 17, Medications for the treatment of obesity in adolescents. Ther Adv Endocrinol Metab. Cardiovascular safety during and after use of phentermine and topiramate.
J Clin Endocrinol Metab. Long-term efficacy and safety of anti-obesity treatment: Where do we stand? Curr Obes Rep. Use of topiramate in pregnancy and risk of oral clefts. Am J Obstet Gynecol. Important Safety Information. Published Centers for Disease Control and Prevention. Losing weight.
Updated February 13, The FDA's assessment of two drugs for chronic weight management. N Engl J Med. Your Privacy Rights. To change or withdraw your consent choices for VerywellFit.
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