Your risk of developing a spinal or epidural blood clot is higher if:. If you take PRADAXA and receive spinal anesthesia or have a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots. Tell your doctor right away if you have back pain, tingling, numbness, muscle weakness especially in your legs and feet , loss of control of the bowels or bladder incontinence.
Tell your healthcare provider or get medical help right away if you get any of the following symptoms of a serious allergic reaction to PRADAXA Capsules:. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
For more information, ask your doctor or pharmacist and be sure to also access the Medication Guide. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. Dabigatran On this page About dabigatran Key facts Who can and cannot take dabigatran How and when to take it Bleeding and what to do about it Other side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.
About dabigatran Dabigatran is a type of medicine known as an anticoagulant, or blood thinner. It's used to treat people who have had a health problem caused by a blood clot, such as: a stroke a heart attack a blood clot in the leg deep vein thrombosis, or DVT a blood clot in the lungs pulmonary embolism It's also used to prevent blood clots if you're at high risk of having them in the future.
People who are at high risk include those who have: an abnormal heartbeat atrial fibrillation recently had surgery to replace a hip or knee joint Dabigatran is only available on prescription.
It comes as capsules. Help us improve our website Can you answer a quick question about your visit today? It's usual to take dabigatran twice a day. You can take dabigatran with or without food.
The most common side effect of dabigatran is bleeding more easily than normal, such as having nosebleeds, bleeding gums and bruising. It tends to happen in the first few weeks of treatment or if you're unwell.
Always carry your anticoagulant alert card with you. Show it to your doctor or dentist before you have surgery or dental treatment. It's important they know you're taking dabigatran, as it may put you at risk of bleeding. Dabigatran is also called by the brand name Pradaxa. Dabigatran can be taken by adults aged 18 and over. Tell your doctor if you: have had an allergic reaction to dabigatran or any other medicines in the past are trying to get pregnant or you're already pregnant — dabigatran can be harmful to your baby have liver problems are taking any other medicines that affect blood clotting, such as warfarin have any injuries that are currently bleeding a lot such as a wound have a stomach ulcer have had a recent spinal injury or surgery have ever had surgery to replace a heart valve are taking the herbal remedy St John's wort often taken for depression have antiphospholipid syndrome , a condition that affects the immune system and makes you more likely to get blood clots.
It's very important to take dabigatran as your doctor advises. If you have trouble swallowing pills, speak to your doctor or pharmacist. Dosage Your dose of dabigatran depends on why you're taking it. This includes if you: are aged 75 years or older take verapamil a medicine for high blood pressure have problems with your kidneys, stomach or throat If you're unsure what dose you need to take, check with your pharmacist or doctor.
What if I forget to take it? What you need to do depends on why you're taking dabigatran. If you often forget doses, it may help to set an alarm to remind you. What if I take too much? How long will I take it for?
If you're taking it for: a knee joint replacement — you'll probably take dabigatran for 10 days a hip joint replacement — it's usual to take dabigatran for 4 to 5 weeks a blood clot — depending on what caused the blood clot, you'll normally take dabigatran for at least 3 months atrial fibrillation — you might need to take dabigatran long term or even for the rest of your life Anticoagulant alert card Your doctor or pharmacist will give you an anticoagulant alert card. Switching from warfarin to dabigatran If you need to switch from warfarin to dabigatran, your doctor will advise you when to stop taking warfarin.
This will probably be a few days before you start dabigatran. This is to help decide exactly when you should start taking dabigatran. Switching from dabigatran to warfarin If you need to switch from dabigatran to warfarin, you may need to take both medicines together for a few days. This is to help decide exactly when you should stop taking dabigatran.
Less serious bleeding It's usual to bleed more easily than normal while you're taking dabigatran. The kind of bleeding you might have includes: periods that are heavier and last longer than normal bleeding for a little longer than usual if you cut yourself occasional nosebleeds that last for less than 10 minutes bleeding from your gums when you brush your teeth bruises that come up more easily and take longer to fade than usual This type of bleeding is not dangerous and should stop by itself.
Things you can do to help yourself Cuts — press on the cut for 10 minutes with a clean cloth. Nosebleeds — find out how to stop a nosebleed or watch this video on stopping nosebleeds. Bleeding gums — if your gums are bleeding, try using a soft toothbrush and waxed dental floss to clean your teeth. Bruises — these are harmless, but can be unsightly. It might help to make them fade more quickly if you put an ice pack wrapped in a towel over the bruise for 10 minutes at a time several times a day.
What you can do to prevent bleeding While you're taking dabigatran, be careful when you do activities that might cause an injury or a cut or bruising. It can help to: avoid playing contact sports or other activities than can cause an injury, such as football, rugby, hockey and horse riding wear gloves when you use sharp objects like scissors, knives and gardening tools stop wet shaving or removing hair with wax - use an electric razor or hair-removing cream instead take dentures false teeth or retainers out for a few hours a day, if you wear them, to give your gums a rest — do not wear dentures or retainers that do not fit properly tell your doctor, dentist or nurse that you take dabigatran before you have any medical or dental procedures or surgery — this includes vaccinations and routine appointments with the dental hygienist Serious bleeding Occasionally, you can have serious bleeding from taking dabigatran.
This can be dangerous and needs urgent medical attention. If you experience serious bleeding, stop taking dabigatran. Very rarely, dabigatran can lead to bleeding in the brain. Common side effects These common side effects happen in more than 1 in people. They're usually mild and do not last long, but talk to your doctor or pharmacist if these side effects bother you or do not go away: tiredness and lack of energy, shortness of breath, noticeable heartbeats heart palpitations and pale skin - these can be signs of anaemia feeling dizzy or lightheaded feeling or being sick nausea or vomiting stomach pain or indigestion Serious allergic reaction In rare cases, dabigatran can cause a serious allergic reaction anaphylaxis.
Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. The Michigan research team noted that there are many medical conditions and situations where taking both aspirin and a DOAC has not been adequately studied. They plan to confirm their findings in a larger, longer study because a low number of blood clots occurred during their study period, possibly hampering their ability to assess if aspirin could be beneficial, Schaefer said.
In prior research, he and Barnes have also found that people taking both aspirin and warfarin, a different kind of anticoagulant, were also at an increased risk of adverse outcomes. The U. Agency for Healthcare Research and Quality has more on blood thinners. Acquire the license to the best health content in the world. The research involved adults taking direct oral anticoagulants DOACs , including apixaban, dabigatran, edoxaban, and rivaroxaban.
Some participants were transitioning to a DOAC from warfarin, another type of anticoagulant. All participants were undergoing treatment for atrial fibrillation or venous thromboembolic disease.
Of the 3, study participants, 1, took daily low-dose aspirin with their DOAC even though there was no clear indication for doing so. Another 2, participants took their DOAC alone. After a minimum of 3 months follow-up, the researchers found an association between DOACs plus low-dose aspirin and increased bleeding events as well as hospital admissions related to bleeding. Blood thinners are typically prescribed to help prevent blood clots. But researchers observed no clear benefit to taking daily aspirin with a DOAC.
Clotting events between the two groups were similar. This was an observational study limited to people in Michigan. Study authors caution there are different subgroups and clinical scenarios where this has not been sufficiently studied.
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